Hodgkin’s disease, mixed cellularity: immunohistochemical staining for CD15. Note the mixed cellular membrane staining and characteristic staining of paranuclear hofs of Reed Sternberg cells. CD15: clone MMA
CD15
Antigen Background
CD15 antigen, also known as X-hapten, is reported to be expressed on 90% of circulating human granulocytes, 30-60% of circulating monocytes and is absent from normal lymphocytes. The CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin’s disease and some leukemias.
Disclaimer
CD15 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
Clone:
Pathology Menu:
Configuration:
HD (High Definition):
Volume:
MMA
Hematopathology
BOND RTU
No
7ml
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Source:
Species:
Regulatory Status:
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use