Human small bowel: immunohistochemical staining for Chromogranin A. Note cytoplasmic staining of neuroedocrine cells. Chromogranin A: clone 5H7
Chromogranin A
Antigen Background
Chromogranin A is a 68 kD acidic protein which is reported to be widely expressed in neural tissues and in secretory granules of human endocrine cells, for example, parathyroid gland, adrenal medulla, anterior pituitary gland, islet cells of the pancreas and C cells of the thyroid. Chromogranin A expression has been reported in neuroendocrine tumors such as pituitary adenomas, islet cell tumors, phaeochromocytomas, medullary thyroid carcinomas, Merkel cell tumors and carcinoids.
Disclaimer
Chromogranin A is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
Clone:
Pathology Menu:
Configuration:
HD (High Definition):
Volume:
5H7
Head, Neck and Endocrine
BOND RTU
No
7ml
Use:
Source:
Species:
Regulatory Status:
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use