The Aperio GT 450 enables histotechnicians to complete scanning tasks quickly and with confidence leveraging a 32-second scan speed*. Output 81 slides/hr at 40x* delivering high quality images with Leica optics and with an IT architecture that is secure and scalable. From the pathology lab to the IT room, the Aperio GT 450 is designed to scale up digital pathology operations. Improve case turnaround with no touch during scanning and continous loading of the racks directly from the HistoCore Workstation (Stainer & Coverslipper) Help increase IT security and control with a dedicated SAM (Scanner Admin Manager) server and software that allows you to set up and monitor multiple Aperio GT 450s at a time. No more single workstations for each scanner Ensure excellent image quality with Leica optics No touch continuous loading during scanning Automated IQ checks during each scan to ensure quality Assign priority cases Every slide is calibrated with each scan 450 slide capacity packed into a small size fits on the lab bench 99.5% accurate tissue finder that allows you to adjust if needed* 100% first-time barcode scan success rate*

ntroducing the Aperio AT2 DX System, a 400 slide scanner with Aperio ImageScope DX clinical viewing software, and a high-performance viewing workstation including color-calibrated medical grade monitors. The system can be used standalone, or in conjunction with Aperio Path DX case management software, for a streamlined, clinical workflow. Developed with proven technology from Leica Biosystems, the Aperio AT2 DX System enables high volume clinical labs to produce consistent, diagnostic quality images, enabling pathologists to diagnose with confidence. TAKE CONTROL OF YOUR TIME IN THE LAB 198% first time scan success Automated tissue finder 20x, 40x scanning options Z-stacking & manual adjustment for difficult samples Eliminate glass slide shipping & carrying DELIVER A CONFIDENT DIAGNOSIS Proven diagnostic quality Medical grade monitors with custom ICC color calibration Barcode linked for case assignment Seamless integration to case workflow

The Leica IC90 E CMOS microscope camera for stereo microscopes was developed for the Leica M series stereo microscopes. It provides pin-sharp images with spot-on color reproduction for professional visualization and documentation of industrial applications. Reveal more details with the 10megapixel resolution Directly connect to your microscope, no documentation tube needed. Connectivity made easy: Ethetnet, USB, HDMI The Leica IC90 E is designed to directly interface with your microscope. It is mounted between the tube and the optics carrier, so you don’t need a documentation tube nor a c-mount to operate the camera.

The Leica DFC3000 G is a grayscale USB 3.0 microscope camera for routine fluorescence applications. You will receive crisp images due to its unique passive cooling architecture and its highly sensitive CCD sensor. Correlated pixel double sampling together with a reduction of the ambient temperature of the sensor offers an exceptionally clear and noise -free signal. Its CCD sensor is particularly suitable for low light situations such as fluorescence and will capture even smallest amounts of light. Contrast Method: Fluorescence Passive cooling system with pixel double sampling and enhanced temperature convection Adaptable digitalization with 8, 12, and 16 bit Professional fluorescence documentation provided by a high-sensitivity 1.3megapixel CCD monochrome sensor from Sony® with micro lenses.

The K5 (grayscale) is ideal for routine fluorescence imaging applications such as immunostaining assays and 3D Cell Culture imaging. Image a wide variety of sample types with the flexibility and power of high 4.2megapixel resolution and fast 40 fps imaging brought to you by the K5. Contrast Method: Fluorescence Cooling method Passive cooling. Bring the flexibility and power of sCMOS technology into your lab and image the details of your experiment. Efficiently segment crucial real time events Improve signal-to-background of your THUNDER Imager. Reduce exposure times and phototoxic effects with high 80% quantum efficiency .

The DMC5400 color CMOS camera offers high frame rate & high-resolution color images even at low magnification. It is optimized to produce fast, high quality images for documentation, evaluation and analysis, for a wide variety of samples and applications in manufacturing and life science research. Contrast Method: BF →PH, DF, DIC, POL, IMC. Capture high-resolution images with 20 Megapixel sensor. Collect high-speed live images at up to 40 frames per second. See natural colors with unsurpassed accuracy. Easily connect with notebooks and PCs via USB 3.0 interface.

Leica DMC4500 color camera. It has been designed as a versatile, uncomplicated tool that simplifies the imaging process from capture through to processing. It is ideally suited to life science applications such as documenting slides and organisms, pathology or pharmaceutical testing and industrial applications such as quality control and failure analysis. Contrast Method: BF → PH, DF, DIC, POL, IMC USB 3.0 interface 5 megapixel CCD sensor Live image speed of up to 18 frames per second SXGA resolution of 1280 x 960 pixels

The Leica DMC2900 is a digital USB 3.0 microscope camera with a 3.1 Megapixel CMOS sensor. It is an ideal tool for brightfield microscopic standard applications in research, life science and industry that often require capturing, documenting, and analyzing color images at optimum visibility of microstructures in little time. The Leica DMC2900 is a digital USB 3.0 microscope camera with a 3.1 Megapixel CMOS sensor. It is an ideal tool for brightfield microscopic standard applications in research, life science and industry that often require capturing, documenting, and analyzing color images at optimum visibility of microstructures in little time. The HDMI mode allows you to use the camera in stand-alone mode without the need for a PC. Contrast Method: BF → PH, DF, DIC, POL, IMC. 3.1megapixel resolution- Optimal for applications using standard microscopes. Fast live imaging speed of up to 30 frames per second Fast USB 3.0 interface for a direct connection between camera and PC or notebook

The FLEXACAM C1 can be adapted to your workplace setup - simply connect the camera to your monitor or PC and network. Thanks to the 12 MP CMOS sensor and large dynamic range, fine details and true-to-life colors are a given. adaptable microscope camera solution for a wide variety of samples and applications in industry, life science, forensics, and education . The HDMI mode allows you to use the camera in stand-alone mode without the need for a PC. Use the Ethernet mode to work with direct access to your facility's network. Save images directly on a USB stick when the camera is used in stand-alone mode. you can choose the USB mode to connect the camera and software directly with your PC. The FLEXACAM C1 is compatible with most Leica stereo and compound microscopes. Contrast Method: BF → PH, DF, DIC, POL, IMC. The FLEXACAM C1 is compatible with the Leica Application Suite (LAS) X software and its expert modules.

Leica DM2700M The Leica DM2700 M flexible upright microscope system uses LED illumination for all contrast methods: brightfield (BF), darkfield (DF), differential interference contrast (DIC), qualitative polarization (POL), and fluorescence (FLUO) applications. It also offers built-in oblique illumination, which improves the visualization of surface topography and defects. Optionally, the Leica DM2700 M can also be equipped with a transmitted light axis . The Leica DM2700 M is equipped, e.g. with an N PLAN achromatic objective series with magnifications from 5x to 100x, a field of view of 22 mm, a flattened image field, and large working distances . A powerful light source for BF, DF, DIC, POL and oblique illumination For objectives series to choose: HIPlan, NPLAN, PL FLUOTAR, PLAN APO Stage stroke 25 mm Colour-coded Diaphragm Assistant (CCDA) Optional Transmitted Light Incident light: Robust incident light axis with 4-position reflector turret Focusing: 2-gear / 3-gear focusing Macro objective: 40mm of the sample at a glance

Leica DM1750M The Leica DM1750 M is a material microscope designed for rapid, accurate analysis results even for use in rough ambient conditions. Working with the Leica DM1750 M you will see; how simple and reliable microscopy can be. Its robust design contains an excellent optical system and allows the inspection even of larger samples, in brightfield, oblique- or with polarized light. The entire reflected light illumination is carried out with Power-LEDs which allow an inspection with different illumination angles, especially suitable for the detection of micro-scratches or for gaining height information. Stand type: Materials analysis microscope in the upright configuration for larger samples. With integrated protection and ergonomic features Illumination: High-power LEDs with additional integrated segmented lighting for oblique illumination Contrast methods: Brightfield (RL BF), POL (RL POL), oblique illumination, differential interference contrast (RL DIC) Focus drive: 2-stage, coarse and fine focus, with adjustable precise sample and objective cap Focus drive: 2-stage, coarse and fine focus, with adjustable precise sample and objective cap Objective nosepiece: 6× BF M25 or 7× BF M25

Microscopy – Page 2 – DMI Medical USA

Q: Aperio LV1 — Real-time Digital Pathology System

The Aperio LV1 is a cost-effective solution for research users looking to adopt Digital Pathology. The small footprint and compact design makes the Aperio LV1 an ideal desktop system. With minimal IT requirements and rapid implementation, your Aperio LV1 can be installed in minutes. The intuitive interface, streamlined design and rapid remote control ensures the Aperio LV1 delivers affordable versatility for your research laboratory; helping you to deliver results faster. The Aperio LV1 enables you to share up to 4 live slides with remote colleagues within 15 seconds* or less. Remote users have full control of the instrument and can switch between slides, change magnification (2.5x, 10x, 20x and 40x), move the slide and even adjust the fine focus.

Q: Aperio AT2 – High Volume, Digital Whole Slide Scanning

With its compact size, high capacity autoloader and optimal image quality, the Aperio AT2 slide scanner has set new standards in digital pathology. Aperio AT2 consistently delivers precise, whole slide images with an unparalleled, low rescan rate. Slides are available for remote viewing in less than a minute. With an easy-to-use Pathologist's cockpit, coupled with easy integration into laboratory information systems (LIS), the Aperio AT2 provides an ideal platform for research institutions. The Aperio AT2 runs on the Microsoft Windows 10 operating system.

Q: Leica DFC9000 GT/GTC sCMOS Camera

The Leica DFC9000 sCMOS camera will turn your imagination into reality. This monochrome microscope camera with newest scientific CMOS (sCMOS) sensor technology for fluorescence imaging enables you to image your cells under near-native conditions. Protect your cells with short exposure times Capture highly dynamic processes with high-speed acquisition Get more information in one image with large field of view High quantum efficiency over the entire light spectrum with a maximum of 82% Low read noise of 0.9 e- at 216 MHz pixel clocking rate Cooled sensor; cooling to 0° Celsius by air circulation With a capture-rate of 50 frames per second (fps) via its USB 3.0 interface, the Leica DFC9000 GT is in the fast lane – and we’re talking full frames. Deeply cooled monochrome fluorescence camera for advanced applications like high- speed live cell imaging, FRAP, and ratio measurement with amazing image quality

Q: Leica DFC700 T and DFC700 GT

These cooled 2.8 megapixel cameras provide a new paradigm for camera image quality through truly innovative design. The monochrome DFC7000 GT for demanding fluorescence applications, or the color DFC7000 T developed for both brightfield and fluorescence imaging. Contrast Method: BF →PH, DF, DIC, POL, IMC | Fluorescence |Quantification Monitor fluorochromes like DAPI, FITC up to Cy7, with highly sensitive sensors that can detect signals even in the near-infrared range. Faithful color fidelity with the DFC7000 T uses advanced color interpolation to maintain natural images. Adapt your imaging for different illumination settings with pre-defined correction matrices Capture at outstanding resolution – 4.54 μm pixels can image even the smallest details. Innovative 5 x 5 demosaicing algorithm – only from Leica Microsystems Deeply cooled monochrome fluorescence camera for advanced applications like high- speed live cell imaging, FRAP, and ratio measurement with amazing image quality Deeply cooled sCMOS camera with a combination of high QEmax (82 %), extreme low noise, high dynamic range, large sensor (19 mm), and highspeed acquisition

Q: Leica DMC6400 Pixel Shift Camera

The DMC6200 camera delivers amazing images with intense color detail and contrast - whether at the lowest or highest magnification. Its state-of-the-art CMOS sensor has a 5.86 μm pixel size, 2.3 megapixels sensor resolution, and an astounding dynamic range of 73 dB (4000:1). Achieve an image resolution of up to 20.7 megapixels with cutting-edge pixel shift technology. Contrast Method: BF →PH, DF, DIC, POL, IMC | Fluorescence High-speed image acquisition up 60 frames per second. for low-light applications, e.g. in fluorescence. The camera is equipped with a USB 3.0 interface. Excellent resolution with vivid colors.