The modular DMi8 inverted microscope is the heart of the DMi8 S platform solution. For routine to live cell research, the DMi8 S platform is a complete solution. Whether you need to precisely follow the development of a single cell in a dish, screen through multiple assays, obtain single molecule resolution, or tease out behaviors of complex processes, a DMi8 S system will enable you to see more, see faster, and find the hidden. Flexibility is built-in, allowing you to add established options like DIC for unstained samples and Intelligent Automation. For time-lapse experiments use precise focus control with Adaptive Focus Control and Closed Loop FocusThis novel design facilitates the integration of additional fluorescence light sources and laser systems for advanced applications like: FRAP photo-switching ablation optogenetics Every DMi8 comes standard with 19mm field of view (FOV) for all camera ports. Configure your system with a variety of contrast method, add sophisticated modalities like TIRF

With Leica EM VCT500 you can transfer samples under cryogenic conditions or at room temperature as well as under vacuum or protected atmosphere.

Microscopy – Page 5 – DMI Medical USA

Q: Leica AC20 | Automatic contrasting instrument for ultrathin sections

The Leica EM AC20 automatic contrasting system for ultrathin sections ensures minimum user contact with reagents and reduced reagent consumption. Usage of a peristaltic pump and non-contact valves allow the reagents to travel directly through tubing to the grid chamber, resulting in fast, high-quality double staining and easy maintenance

Q: Leica EM TP | Tissue Processor

The Leica EM TP is an instrument used for fixation and dehydration of samples for further treatment. It can be used for resin processing for electron microscopy (EM) and light microscopy (LM). The Leica EM TP consists of a base unit onto which an EM or LM processing outfit can be added. Interchange between EM or LM processing takes only moments. Reagents can be pre-loaded into the vials attached to the carousel in a fume cupboard. Toxic reagents can be sealed with individual vial caps before taking them over to the Leica EM TP. The TP chamber is also ventilated via a fume extraction system

Q: Leica EM RES102 | Ion Beam Milling System

Unique ion beam milling device with two modified saddle field ion sources of variable ion energy for optimum results. It combines the preparation of TEM, SEM, and LM samples in a single benchtop unit. A variety of sample holders allows a diverse range of applications to be carried out. In addition to high-energy ion beam milling, the Leica EM RES102 can also be used for very gentle sample processing using low ion energy.

Q: Leica EM TIC 3X | Ion Beam Milling System

The Triple Ion Beam Milling System, EM TIC 3X allows production of cross sections and planar surfaces for Scanning Electron Microscopy (SEM), Microstructure Analysis (EDS, WDS, Auger, EBSD) and AFM investigations. With the EM TIC 3X you achieve high quality surfaces of almost any material at room temperature or cryo, revealing the internal structures of the sample in a near native state as possible. the Leica EM TIC 3X can be configured for applications of standard preparation, high throughput processing, and the preparation of extremely heat sensitive samples such as polymers, rubbers, or even biological material at low temperatures. Samples can be transferred to the (cryo) SEM under cryo-vacuum condition

Q: Leica EM TRIM2 | Specimen Trimming Device for SEM TEM & LM

The Leica EM TRIM2 is a high-speed milling system with integrated stereomicroscope and LED ring illuminator for trimming of biological and industrial samples prior to ultramicrotomy. The Leica TRIM2 features a 1µm feed control for the milling cutter, perpendicular viewing of the embedded sample to determine position for accurate milling, and a superior extraction system with Hepa filter.

Q: Leica EM Rapid | Pharmaceutical Milling System for Pills

The Leica EM RAPID milling system for pharmaceutical research enables sample preparation for analysis of active ingredient distribution on solid-dose pharmaceuticals. The instrument, using a tungsten carbide or diamond miller, decapsulates pills without smearing and features adjustable cutting speeds between 300 and 20,000 rpm, defined step-layer removal, low-noise extraction, and filtration with a Hepa filter and single or multiple holders.

Q: Leica EM TXP | Target Surfacing System

The Leica EM TXP is a target preparation device for milling, sawing, grinding, and polishing samples prior to examination by SEM, TEM, and LM techniques. An integrated stereomicroscope allows pinpointing and easy preparation of barely visible targets. With the specimen pivot arm the sample can be observed directly at an angle between 0° and 60°, or 90° to the front face for distance determination with an eyepiece graticule

Q: Leica EM ACE900 | Freeze Fracturing System

The Leica EM ACE900 is a high-end sample preparation system for freeze fracturing, freeze etching and high resolution cryo coating. This instrument is easy and intuitive to use. To achieve highest sample protection sample transfer, large cryo-shields, and the sample shutter are optimized. Users obtain best results because the instrument stays always in high vacuum. This is provided by a load lock system, a knife transfer, and gate valves for each e-beam source. The perfect combination of automation and optional manual operation makes the preparation process highly reproducible and flexible. Versatility, speed, and yield of your sample preparation is incomparable

Q: Leica EM CDT | Cryo Tool Drying

During Cryo preparation, tools such as forceps and sample holders often ice over and cannot be immediately used for the next sample run. De-icing and drying of the tools at room temperature is time consuming and can cause damage to sensitive components and may prevent their operation. The special combination of heated air flow and heating plate completely dries tools, even on their difficult to access inner surfaces. The maximum temperature of + 50°C ensures that the cryo tools dry without heat damage and protect the user from the risk of burns