Producing homogenous and conductive metal or carbon coatings for SEM and TEM analysis was never more convenient than with the Leica EM ACE200 coating system. Configured as a sputter coater or carbon thread evaporation coater, perfectly reproducible results can be achieved in the fully automated system. If both methods are required for your analysis Leica Microsystems offers a combined instrument with interchangeable heads in one instrument. Various options as Quartz Crystal Measurement, Planetary Rotation, Glow Discharge, and Exchangeable Shielding complete this Low Vacuum Coater.

The EM ACE600 is a versatile high vacuum film deposition system, designed to produce very thin, fine-grained, and conductive metal and carbon coatings for the highest resolution analysis, as required for FE-SEM and TEM applications. This fully automated table-top coater includes an integrated oil-free pumping system, quartz crystal film thickness measurement and three axis motorized stage (rotation, optional tilt and height).

The CABINETS of SERIES AV-017 are designed in compliance with the current regulations regarding safety at work. In the case of cabinets with ascending aspiration, the operation is based on an air circulation system generated by a compact suction unit located in the upper area of the cabinet. In cabinets with downward aspiration, the equipment is located at the bottom. Although the structural configuration can vary in each case, the design of the operation is the same for all models of the SERIES AV-017. In this way, contaminated air is drawn from inside the cabinet, and is conducted to a specific filter, which allows the extracted air to be evacuated in a clean and safe manner.

The Leica DM IL LED features a comprehensive set of contrast methods to monitor your specimen the way you need. High-quality Phase contrast, excellent modulation contrast and brilliant fluorescence are just one fingertip away. Robust stability, plenty of space to work with tools, long working distances to accommodate large culture flasks and a stable illumination without heat make work at the microscope easy and convenient For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) including in-vitro-fertilization (IVF).

The modular DMi8 inverted microscope is the heart of the DMi8 S platform solution. For routine to live cell research, the DMi8 S platform is a complete solution. Whether you need to precisely follow the development of a single cell in a dish, screen through multiple assays, obtain single molecule resolution, or tease out behaviors of complex processes, a DMi8 S system will enable you to see more, see faster, and find the hidden. Flexibility is built-in, allowing you to add established options like DIC for unstained samples and Intelligent Automation. For time-lapse experiments use precise focus control with Adaptive Focus Control and Closed Loop FocusThis novel design facilitates the integration of additional fluorescence light sources and laser systems for advanced applications like: FRAP photo-switching ablation optogenetics Every DMi8 comes standard with 19mm field of view (FOV) for all camera ports. Configure your system with a variety of contrast method, add sophisticated modalities like TIRF

The Leica M320 F12 with LED - a highlight for ENT applications. The Leica M320 F12 bundles apochromatic optical quality with cutting-edge LED illumination and high-definition imaging technology. Ease of use and flexible, smooth maneuverability are additional characteristics of this microscope. With the Leica M320 F12, Leica Microsystems has created a new industry standard with a variety of unique benefits for ENT surgeons. Cost-effective & sustainable with a lifetime of about 60000 hours, LED lighting reduces the cos microscope ownership and eliminates retrofit expenses. Better efficiency Binocular tubes, objective lenses, handles, and the vibration-free microscope arm can be situatively customized to suit the surgeon's preferences and specializations. Hygienically sound The Leica M320 is virtually jointless. All cables are routed internally handles can be washed and sterilized. The surface is protected with permanent antimicrobial coating, Agprotect. High definition documentation Patients and healthcare professionals are now optimally involved in the consultation and treatment. A further highlight, all data can be saved on a SD Memory Card.

Products – Page 5 – DMI Medical USA

Q: Leica EM ICE | High Pressure Freezer

High pressure freezing is key for the study of intricate changes in fine structure or cellular dynamics. Cryo-immobilize your aqueous samples under high pressure with a unique freezing principle and uncover secrets of the cellular process. Capture and resolve highly dynamic processes at the nanometer scale with millisecond precision. The EM ICE solution, combining superior high pressure freezing with the possibility of light and electrical stimulation, is the platform for your discoveries LN 2 Consumption Value LN 2 consumption during cool down 80lts 8 liters LN 2 consumption in operation including cool down 30lts 30 liters LN 2 consumption per freezing process 80ml 80 ml

Q: Leica EM GP2 | Automatic Plunge Freezer

The EM GP2 plunge freezes fluid or extremely thin samples spread on an electron microscopy grid into liquid ethane after removing excess fluid by automatic blotting. Prior to freezing the sample is maintained in a temperature and humidity controlled environmental chamber, adjustable between +4°C and +60°C and room humidity to 99 %. Safe and reproducible preparation for single particle analysis and cryo-tomography.

Q: Leica EM AFS2 and EM FSP

Freeze Substitution and Low Temperature Embedding System The Leica EM AFS2 performs freeze substitution and progressive lowering of temperature (PLT) techniques and allows low temperature embedding and polymerization of resins. The Leica EM FSP (freeze substitution processor), an automatic reagent handling system combined with the Leica EM AFS2, dispenses reagents for both freeze substitution and PLT applications. The LED illumination from within the chamber and the attached stereomicroscope for viewing and positioning of samples ensures ease of use Reduces set-up time Automatic dilution of reagents from 100% stock containers reduces user reagent handling and set-up time. Specimens remain dry Adjustable transfer function of gaseous LN2 allows the chamber and specimens to remain dry, which results in no contamination of the specimen One Step preparation Fast UV polymerization with LED UV lamp results in one-step preparation for the user; samples and reagents can be added and left until the end of the run –140 °C to +70 °C working range AFS smart-remote observation of the process and delivery of critical information via SMS Stereomicroscope viewing

Q: Leica EM CDT | Cryo Tool Drying

During Cryo preparation, tools such as forceps and sample holders often ice over and cannot be immediately used for the next sample run. De-icing and drying of the tools at room temperature is time consuming and can cause damage to sensitive components and may prevent their operation. The special combination of heated air flow and heating plate completely dries tools, even on their difficult to access inner surfaces. The maximum temperature of + 50°C ensures that the cryo tools dry without heat damage and protect the user from the risk of burns

Q: Leica EM ACE900 | Freeze Fracturing System

The Leica EM ACE900 is a high-end sample preparation system for freeze fracturing, freeze etching and high resolution cryo coating. This instrument is easy and intuitive to use. To achieve highest sample protection sample transfer, large cryo-shields, and the sample shutter are optimized. Users obtain best results because the instrument stays always in high vacuum. This is provided by a load lock system, a knife transfer, and gate valves for each e-beam source. The perfect combination of automation and optional manual operation makes the preparation process highly reproducible and flexible. Versatility, speed, and yield of your sample preparation is incomparable

Q: Leica EM TXP | Target Surfacing System

The Leica EM TXP is a target preparation device for milling, sawing, grinding, and polishing samples prior to examination by SEM, TEM, and LM techniques. An integrated stereomicroscope allows pinpointing and easy preparation of barely visible targets. With the specimen pivot arm the sample can be observed directly at an angle between 0° and 60°, or 90° to the front face for distance determination with an eyepiece graticule

Q: Leica EM Rapid | Pharmaceutical Milling System for Pills

The Leica EM RAPID milling system for pharmaceutical research enables sample preparation for analysis of active ingredient distribution on solid-dose pharmaceuticals. The instrument, using a tungsten carbide or diamond miller, decapsulates pills without smearing and features adjustable cutting speeds between 300 and 20,000 rpm, defined step-layer removal, low-noise extraction, and filtration with a Hepa filter and single or multiple holders.

Q: Leica EM TRIM2 | Specimen Trimming Device for SEM TEM & LM

The Leica EM TRIM2 is a high-speed milling system with integrated stereomicroscope and LED ring illuminator for trimming of biological and industrial samples prior to ultramicrotomy. The Leica TRIM2 features a 1µm feed control for the milling cutter, perpendicular viewing of the embedded sample to determine position for accurate milling, and a superior extraction system with Hepa filter.