The Leica DM500 microscope with “plug and play” capability is the ideal tool to make teaching entry-level college and university Life Science courses easy and fun for the instructor and the student. The Leica DM750 is the ideal microscope for the versatile needs of advanced college and university life science courses and professional training in medical, veterinary and dental schools. EZStore™ design Auto Off (DM750) EZLite™ – provides over 20 years of bright, LED illumination which saves time and the cost of replacement bulbs. AgTreat™ – all touchpoints treated to prevent bacteria spreading from student to student. For: Brightfield (BF), Phase Contrast (PH), Darkfield (DF), Fluo (FL), Basic POL Plan-Acrhomatics objectives

The Leica DM1000 LED features long-life LED illumination that provides near daylight, bright illumination with constant colour temperature and emits less heat. The LED also eliminates the need for lamp changes, which saves time and money. Because of its low power consumption, the system is energy efficient. Users of the Leica DM1000 LED benefit from the system’s ability to uniquely adapt to every user. It is ideal for all clinical laboratory applications, especially for cytology, haematology, and pathology . For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF). For: Brightfield (BF), Phase Contrast (PH), Darkfield (DF), Fluo (FL), Basic POL Objectives HiPlan / NPlan / PL Fluotar Nosepiece 5-fold Koehler Illumination Koehler Illumination Wide range of accessories

With their sophisticated modular design and high-performance fluorescence , the Leica DM2000 microscopes are ideal for complex tasks in pathology, cytology , and many other applications. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF). The Leica DM2000 microscopes can be configured with a variety of optics and contrast techniques to meet the specific requirements of demanding applications. Leica DM2000 is available in two versions, with bright halogen illumination, or with long-life LED. For: Brightfield (BF), Phase Contrast (PH), Darkfield (DF), Fluo (FL), POL Objectives Hi Plan / NPlan / PL Fluotar /PL APO Nosepiece 5 or 6 fold Koehler Illumination Height-adjustable focus knobs Wide range of accessories Integrated Adjustable Controls

Leica DM2500 & DM2500 LED optical microscopes are tools for demanding tasks in life science routine and research applications. With their transmitted light illumination, optical performance, and state-of-the-art accessories, they are especially well-suited for challenging life science research tasks that require differential interference contrast or high-performance fluorescence. The difference between the two optical microscopes is their illumination: DM2500 LED is equipped with LED illumination for transmitted light, DM2500 works with halogen. Both types of illumination render a realistic impression of the colours of the sample, so that users in clinical applications, such as the frequently used HE specimen staining, are able to assess the colours of their samples accurately. Designed with application-oriented modularity, the DM2500 & DM2500 LED can be configured to fit a wide variety of applications and accommodate the diverse physical requirements of individual users. For: Brightfield (BF), Phase Contrast (PH), Darkfield (DF), Fluo (FL), Advance POL, DIC Large selection of high class objectives Nosepiece 6 or 7 fold Koehler Illumination Height-adjustable focus knobs Wide range of accessories Integrated Adjustable Controls

The Leica DM3000 microscopes for pathology, cytology, haematology and many other applications feature a motorized nosepiece, condenser head, automated light intensity adjustment, and optional foot pedal . These intuitive microscopes improve workflows significantly. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF). The motorized condenser head knows the correct position for each magnification. The Leica DM3000 automatically adjusts the light intensity to each objective’s requirements, stores previously used light values for each magnification, and boosts efficiency when changing between two magnifications thanks to its unique toggle mode. For: Brightfield (BF), Phase Contrast (PH), Darkfield (DF), Fluo (FL), POL Large selection of high class objectives Motorized Nosepiece 6 Automated light adjustment Koehler Illumination Height-adjustable focus knobs Wide range of accessories Integrated Adjustable Controls Freely programmable control buttons

Increase your work efficiency with the Leica DM4 B or Leica DM6 B upright digital research microscopes! Both are ideally suited to making your work life easier in biomedical research and clinical labs alike. You can configure the microscope that fits your need and budget with the Leica DM4 B and Leica DM6 B. Optimize your system to your application with different contrast methods and automated functions. Simplify your workflow with automated functions and easy-to-use software. Easily capture publication-quality images by utilizing the 19-mm sCMOS camera imaging port Create fast overviews of your samples and identify the important details instantly with the LAS X Navigator Software Have great flexibility through the choice of accessories. Automated Upright Microscope System for Life Science and Clinical Applications Leica DM4 B Fully Automated Upright Microscope System for Life Science Research Leica DM6 B Transmitted Light Contrast Methods BF, PH, DF, POL, DIC Fluorescence Axis: Fully Automated Focus: Mechanical (DM4) / Mechanical or Motorized (DM6) LCD Display LAS X Navigator Software

Do you work in a field such as electrophysiology, evolutionary biology, or neuroscience where outstanding stability is required for successful experiments? The Leica DM6 FS fixed stage fluorescence microscope is a suitable instrument for your present and future challenges. Perform your experiment with a high degree of mechanical and electronic stability. Save time using the microscope’s full range of automated functions. Efficiently work with tools and accessories using special Leica optics that provide ample clearance around the specimen Add special techniques based on the Leica DM6 FS for Optogenetics and Cryo CLEM Vibration-free Operation

Laser Microdissection Microscopes Leica LMD6 & LMD7

Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes. LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next-generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live-cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis. We move the laser, not the sample. And we use gravity for collection. That is why our LMD systems provide you with perfectly cut, contamination-free, analysis-ready dissertates.

THUNDER Imager Tissue

The THUNDER Imager Tissue allows real-time fluorescence imaging of 3D tissue sections typically used in neuroscience and histology research. Acquire rich, detailed images of thick tissues free of haze from out-of-focus blur. Even fine structures deep in tissues can be resolved thanks to Computational Clearing, an innovative Leica technology. Image detailed morphological structures like axons and dendrites of neurons in a brain slice. The high image quality, even with thick tissue sections, is combined with the well-known speed, fluorescence efficiency, and ease of use of widefield microscopes. Gain these advantages using a THUNDER Imager Tissue for your research: Rapidly acquire blur-free images showing the finest details of the morphology, even deep within thick sections Get fast overviews of whole tissue sections Image and analyze challenging tissue sections with an easy workflow Two Options for THUNDER Imager Tissue Choose the configuration which best meets your requirements: THUNDER Imager 3D Tissue is a fully automated tissue imaging system for recording multi-color 3D images. Capture multiple images in the z-direction and visualize them in the 3D viewer. Achieve excellent z-stack imaging due to a precise motorized focus drive. Decode 3D structures in real time. For brilliant imaging of single planes and fast overviews of your tissue the THUNDER Imager Tissue is also available in a cost-effective configuration without a motorized focus drive.

Leica DM 1000 | Fluo-axis for 3 excitation cubes

Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy, mainly because of its high sensitivity and high specificity. Fluorescence is a form of luminescence. Fluorescence microscopy even allows users to determine the distribution of a single molecule species, its amount and its localization inside a cell. Colocalization and interaction studies can be performed, and ion concentrations, as well as intra- and intercellular processes like endocytosis and exocytosis, can be observed. With the help of super-resolution fluorescence microscopy, it is even possible to image sub-resolution structures.

Leica DM2000 | Fluo-axis for 4 excitation cubes

Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy, mainly because of its high sensitivity and high specificity. Fluorescence is a form of luminescence. Fluorescence microscopy even allows users to determine the distribution of a single molecule species, its amount and its localization inside a cell. Colocalization and interaction studies can be performed, and ion concentrations, as well as intra- and intercellular processes like endocytosis and exocytosis, can be observed. With the help of super-resolution fluorescence microscopy, it is even possible to image sub-resolution structures.

Leica DM2500 | Fluo-axis for 4 excitation cubes

Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy, mainly because of its high sensitivity and high specificity. Fluorescence is a form of luminescence. Fluorescence microscopy even allows users to determine the distribution of a single molecule species, its amount and its localization inside a cell. Colocalization and interaction studies can be performed, and ion concentrations, as well as intra- and intercellular processes like endocytosis and exocytosis, can be observed. With the help of super-resolution fluorescence microscopy, it is even possible to image sub-resolution structures.

Leica DM4 & DM6 | Motorized Fluo-Axis 5 cubes (DM4); 5 or 8 cubes (DM6)

Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy, mainly because of its high sensitivity and high specificity. Fluorescence is a form of luminescence. Fluorescence microscopy even allows users to determine the distribution of a single molecule species, its amount and its localization inside a cell. Colocalization and interaction studies can be performed, and ion concentrations, as well as intra- and intercellular processes like endocytosis and exocytosis, can be observed. With the help of super-resolution fluorescence microscopy, it is even possible to image sub-resolution structures.

Leica DM ILED | Fluo-axis for 3 excitation cubes

Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy, mainly because of its high sensitivity and high specificity. Fluorescence is a form of luminescence. Fluorescence microscopy even allows users to determine the distribution of a single molecule species, its amount and its localization inside a cell. Colocalization and interaction studies can be performed, and ion concentrations, as well as intra- and intercellular processes like endocytosis and exocytosis, can be observed. With the help of super-resolution fluorescence microscopy, it is even possible to image sub-resolution structures.

Leica DMi8 | Manual or Motorized Fluo-Axis 6 excitation cubes

Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy, mainly because of its high sensitivity and high specificity. Fluorescence is a form of luminescence. Fluorescence microscopy even allows users to determine the distribution of a single molecule species, its amount and its localization inside a cell. Colocalization and interaction studies can be performed, and ion concentrations, as well as intra- and intercellular processes like endocytosis and exocytosis, can be observed. With the help of super-resolution fluorescence microscopy, it is even possible to image sub-resolution structures.

Leica ICC50 W/E for compound microscopes

The ICC50 E exclusively uses the facilities network (WLAN or LAN) to allow students to connect to the camera. This is an ideal solution if you don`t want to add additional Wi-Fi access points to your existing wireless network concept. These 5-megapixel cameras can live-stream HD images to students’ smartphones or tablets. Students can connect to the ICC50 W either through their own internal Wi-Fi signal or through the facilities network. Contrast Method: BF PH, DF Interactive teaching AirTech HDMI high-definition output USB 2.0 connection for PC or Mac

The Leica FS M manually-controlled forensic macroscope provides the flexibility, convenience, and comfort that make it the universal instrument of firearms and tool mark examiner. The versatile system is ideal for the simultaneous observation of evidence for training and consultation. The high-quality comparison bridge supports two precisely matched sets of apochromatically corrected objectives on quintuple ball-bearing nosepieces. Telecentric APO macro Telecentric APO macro objectives with built-in iris diaphragms further enhance contrast and increase the depth of field for the ultimate high contrast reproduction of evidence.

THUNDER Imaging Systems

The time has come for imaging systems that allow you to tackle easily biologically relevant 3D models: THUNDER Imagers. To answer important scientific questions, they enable you to obtain a clear view of details, even deep within an intact sample, in real-time without out-of-focus blur. Sharp imaging of 3D specimens is now as easy as working with your favourite camera-based fluorescence microscope. THUNDER Imagers with Computational Clearing define a new class of instruments for high-speed, high-quality imaging of thick, 3-dimensional specimens. The THUNDER Imager Model Organism allows fast and easy 3D exploration of whole organisms for developmental or molecular biology research • THUNDER Imager Live Cell & 3D Cell Culture & 3D Assay THUNDER Imagers provide you with a solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids. The THUNDER Imager EM Cryo CLEM is a cryo light microscope featuring opto-digital THUNDER technology.

Leica Application Suite (LAS)

The Leica Application Suite (LAS) integrates Leica automated microscopes and digital cameras and provides one common, easy-to-use, consistent user interface. LAS automation provides faster routine and research analysis while allowing manual operation. Real-time, high-resolution imaging is performed for life science and industrial applications such as entomology and quality control. Microscope and digital camera configuration and control in a fully integrated manner. Basic annotation tools allow image and calibration data to be added to images. Auto and manual exposure adjustments allow fully optimized imaging conditions. A thumbnail gallery of acquired images, which can be reviewed quickly and easily. Calibrations calculated from magnification data read from Leica microscopes and cameras; a scalebar indicates image size. Extend LAS capabilities in image acquisition and documentation of single images Leica LAS Extended Annotation Leica LAS Interactive Measurement Leica LAS Live Measurement Leica LAS Reticule Leica LAS MultiTime Leica LAS Multifocus Leica LAS Montage Leica LAS MultiStep Leica LAS Image Builder

For industrial quality control and materials research, your goal is to deliver accurate and reliable results. You need software that enables you to work with speed, efficiency, and precision and facilitates your daily tasks. The Leica Application Suite X (LAS X) software allows you to do straightforward imaging and documentation for industrial applications. Observe your sample over the full screen. Configure the microscope system with individual user profiles. Make streamlined and flexible measurements when doing analysis. Enhance your imaging with stitching in X, Y, and Z Acquire and recall reliable and reproducible results. Customize report templates for your needs.

The Leica LAS EZ software, compatible with the Leica EZ4 W/E stereomicroscope, as well as the Leica EC4, Leica ICC50 W/E and Leica IC90 E digital cameras, provides an ideal common, easy-to-use, consistent platform for basic education, industry and life science applications. The Leica LAS EZ guides the user through the camera settings and shading corrections for high-quality imaging and allows the user to easily make annotations and basic measurements. Free hand annotation on the live and captured images.

Leica LAS X Life Science

Leica Application Suite X (LAS X) is the one software platform for all Leica microscopes: It integrates confocal, widefield, stereo, super-resolution, and light-sheet instruments from Leica Microsystems. Users spend more time researching Imaging tasks become intuitive From basic documentation to advanced life science research – LAS X directly navigates you to brilliant imaging! LAS X supports you in analyzing even complex fluorescence experiments with ease. Create separate analysis channels for each fluorescent marker or color. Assign an individual workflow to each. Run an analysis of all aspects of your sample at the same time, e.g. Count the number of spots per nucleus Count healthy and abnormal cells in two separate channels

Aperio VERSA Brightfield, Fluorescence & FISH Digital Pathology Scanner

The Aperio VERSA is a comprehensive digital pathology scanner, designed and developed to support the diverse imaging needs of cutting edge research facilities. The combination scanner is optimized for precision scanning of brightfield and fluorescent samples, with the accuracy and resolution required for FISH. From tissue-based and proteomic markers, to subcellular, molecular and in-situ hybridization probes, the Aperio VERSA delivers high-resolution, reliable imaging. Users can create a permanent record of their research – even faint fluorescent samples, which are often subject to fading. The Aperio VERSA is ideal for scanning multiplex slides at any magnification from 5x to 63x for the whole slide without the need for spectral imaging. The wide range of objective lenses from 1.25x to 63x, with motorized nose piece for automatic changing, enables users to readily scan slides at their ideal resolution. Scan slides anywhere from 0.9mm to 1.2mm thick1, with scan times of 206 secs2 for 15x15mm at 20x. The automated oiler and oil-immersion lenses for 40x and 63x facilitates capture of the high resolution scans in batch and unattended modes.

Aperio CS2 — High quality digital slides from your desktop

Create high-quality digital slides with the ultra-compact Aperio CS2 image capture device from your desktop. With a five-slide capacity and 20X and 40x magnification capabilities, the Aperio CS2 is a highly reliable workhorse for medium-volume sites. The intuitive interface and easy-to-use design consistently provides rapid creation of high resolution digital slides, with >98% first time scan success rate. The Aperio CS2 runs on the Microsoft Windows 10 operating system. The Aperio CS2 scans and moves images in record time for remote Pathologist review. With a fast 1GB/second network interface, digital slides are ready for review in your eSlide tray in 90 seconds.